Aveo Oncology has posted data from a planned interim analysis of the Phase II study of tivozanib in patients with colorectal cancer (CRC). The data indicate that the study is unlikely to meet the primary endpoint in the intent-to-treat patient population. The trial, led by development partner Astellas, is an open-label, randomized Phase II study with a primary endpoint evaluating the superiority of tivozanib in combination with modified FOLFOX6, a standard chemotherapy, compared to bevacizumab ...